Health & Safety Industry Today

Global Chronic Plaque Psoriasis Market to Grow with Advances in Biologics and Personalized Medicine – BIS Research

The global chronic plaque psoriasis market is experiencing strong growth, fueled by the rising prevalence of autoimmune diseases, increased awareness of psoriasis burden, and adoption of biologic therapies. According to BIS Research, biologics such as IL-17 inhibitors and IL-23 inhibitors are now the mainstay for moderate to severe cases, significantly improving disease control compared to older systemic agents. Topical therapies, PDE4 inhibitors, and TNF-alpha inhibitors remain critical for mild to moderate disease, providing complementary options alongside biologics. Digital health solutions such as AI-driven imaging, mobile health apps, and tele dermatology are also transforming psoriasis management by enabling more accurate assessments, continuous monitoring, and improved adherence. With genetic profiling, biomarker-guided treatment, and combination regimens, psoriasis care is shifting toward a more personalized and holistic approach, ultimately improving both clinical outcomes and quality of life.
Published 29 August 2025

What is Chronic Plaque Psoriasis? 

Chronic plaque psoriasis is a chronic, immune-mediated inflammatory skin condition that affects 2–3% of the global population. It is characterized by red, scaly plaques resulting from accelerated skin cell turnover and immune dysregulation. The disease is strongly associated with autoimmunity, obesity, and genetic predisposition, and often has significant psychological and social impacts. Treatment ranges from topical corticosteroids and systemic agents to advanced biologics and immunotherapies for severe cases. 

What is the Current Market Outlook for Chronic Plaque Psoriasis? 

North America and Europe lead the psoriasis market due to widespread biologic adoption, structured reimbursement systems, and advanced dermatology care networks. Asia-Pacific is emerging as a high-growth region, supported by rising disease awareness, healthcare infrastructure development, and gradual reimbursement improvements. Barriers remain, particularly the high cost of biologics, patient adherence challenges, and limited awareness in low-income regions. According to BIS Research, chronic plaque psoriasis market is set to grow significantly in upcoming years. 

What is the key Innovation & Trends in Chronic Plaque Psoriasis Market? 


  • Rapid uptake of IL-17 and IL-23 inhibitors for moderate to severe psoriasis 
  • Growing role of personalized medicine and genetic profiling for treatment selection 
  • Adoption of AI-based imaging and digital health platforms for disease monitoring 
  • Expansion of combination therapies to improve disease control and reduce relapse 
  • Improved focus on quality of life and mental health alongside clinical outcomes 
  • Strategic partnerships to develop biomarkers and companion diagnostics 


How Does This Report Help Organizations Drive Strategic Growth? 


  • Benchmark drug classes – Compare IL-17, IL-23, PDE4 inhibitors, TNF-alpha inhibitors, and topical steroids. 
  • Evaluate innovation pipelines – Track biologics, biosimilars, biomarkers, and combination regimens. 
  • Identify regional opportunities – Assess adoption trends across North America, Europe, Asia-Pacific, and RoW. 
  • Monitor strategies – Review M&A, partnerships, and digital health collaborations. 
  • Navigate barriers – Address biologic cost, patient adherence, and treatment access challenges. 


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What Are the Demand Driver and Challenges in Chronic Plaque Psoriasis Market? 


Drivers 


  • Rising global prevalence of psoriasis and autoimmune diseases 
  • High demand for biologic therapies in moderate to severe disease 
  • Advances in diagnostic tools, AI imaging, and telemedicine 
  • Increasing use of precision medicine and biomarker-guided treatment 
  • Expanding reimbursement for biologics in developed markets 


Challenges 


  • High cost of biologic therapies limiting access in some regions 
  • Adherence challenges with long-term systemic or biologic use 
  • Lack of awareness and delayed diagnosis in underserved regions 
  • Persistent side effect concerns with ADT, systemic agents, and immunotherapies 


What is the Market Segmentation in the Chronic Plaque Psoriasis Market? 

By Drug Class 

  • Interleukin (IL)-17A Inhibitors 
  • Interleukin (IL)-23 Inhibitors 
  • Phosphodiesterase 4 (PDE4) Inhibitors 
  • Topical Steroids 
  • Tumor Necrosis Factor (TNF)-Alpha Inhibitors 


By Region 

  • North America 
  • Europe 
  • Asia-Pacific 
  • Rest of the World 


What Is the Competitive Landscape in the Chronic Plaque Psoriasis Market? 


Strategic Initiatives 

Novartis, AbbVie, and Janssen are expanding portfolios with next-gen IL-17 and IL-23 inhibitors, while Eli Lilly and Amgen invest in biosimilars and combination regimens. Pharma firms are partnering with digital health startups to integrate AI-based imaging and mobile monitoring apps, supporting personalized care and adherence. 

Here Are Some Case Studies and Success Stories in Chronic Plaque Psoriasis Market 

In the U.S., Skyrizi and Cosentyx showed strong real-world uptake, improving long-term disease control in moderate-to-severe psoriasis. In Europe, AI-based imaging tools were piloted in dermatology clinics, enhancing lesion severity assessment and treatment optimization. In Asia-Pacific, biomarker-guided programs in Japan and Korea supported tailored biologic selection, improving outcomes and reducing relapse rates. 

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About BIS Research 

BIS Research is a global B2B market intelligence and advisory firm focusing on deep technology and related emerging trends, which can disrupt the market dynamics in the near future. We publish over 200 market intelligence studies annually, focusing on several deep technology verticals.   

Our strategic market analysis emphasizes market estimations, technology analysis, emerging high-growth applications, deeply segmented granular country-level market data, and other important market parameters useful in the strategic decision-making for senior management.    

BIS Research offers syndicate and custom studies and expert consultations to firms, providing them with specific and actionable insights on novel technology markets, business models, and competitive landscapes.   


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