Solvent Evaporation Market Driven By BIOTAGE AB, PORVAIR, STEROGLASS, RAYKOL, APRICOT DESIGNS, CRESCENT SCIENTIFIC

Solvent evaporation involves emulsification of polymer in aqueous phase and dispersion in a volatile solvent like dichloromethane, chloroform, and ethyl acetate. Then the solvent is evaporated using high temperature, vacuum, or by continuous stirring. Size of the particles can be controlled by adjusting parameters like manipulating evaporation temperature, controlling the rate of evaporation, manipulating stirring rate, etc. This method is being practiced for the nanoparticles developed using respective polymers such as, PLA, PLGA, PCL, polyhydroxybutyrate, etc. loaded with various drugs like tetanus toxoid, testosterone, loperamide, cyclosporin A, and indomethacin. Solvent evaporators are widely used in processes such as microencapsulation and are required to prepare polymeric nanoparticles for various pharmaceutical formulations. Technological advancements in solvent evaporation systems, such as centrifugal concentration, freeze-drying, and high-power cold traps, have led to enhanced evaporation and improved solvent recovery, with lesser environmental impact.

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The growth of the solvent evaporation market is driven by key driving factors such as increasing expenditure on R&D, growing development of large-molecule biopharmaceuticals, and surging demand for pure samples in end-use markets. However, inaccuracies in results and wastage of resources due to uneasiness associated with solvent evaporation hinder the market growth. Buchi Labortechnik AG; Biotage AB; Labconco Corporation; Heidolph Instruments GmbH & Co. Kg; Yamato Scientific Co., Ltd.; Porvair Plc; IKA Works GmbH and Co. KG; Steroglass SRL; Organomation Associates, Inc.; KNF Neuberger, Inc.; Raykol, Apricot Designs, Inc.; Labtech S.R.L.; Crescent Scientific; and Scinco Co., Ltd. are among the major companies operating in the market.

Based on type, the global solvent evaporation market is segmented into rotary evaporators, nitrogen blowdown evaporators, centrifugal evaporators, and spiral air flow evaporators. The rotary evaporators segment held the largest share of the market in 2020. However, the nitrogen blowdown evaporators segment is estimated to register the highest CAGR of 7.4% in the market during the forecast period. The rotary evaporator plays a major role in efficient extraction of solvent through evaporation which is an important step in developing pure samples in several industries. The factors such as increasing R&D expenditures and several benefits associated with this technique are propelling the growth of the solvent evaporation market.

Solvent evaporation active substances are an essential step in the drug discovery process, as it is used in stages such as synthesis, sample preparation, and solvent recycling, as well as in the production scale-up of novel therapeutics. Many pharmaceutical companies invest huge amounts in research and development (R&D) process that mainly revolves around discovering and developing innovative molecules. According to a report published in Statista, the global spending on pharmaceutical R&D totaled US$ ~181 billion in 2018, and it expected to reach US$ 223 billion by 2026. As per the India Brand Equity Foundation, Indian pharmaceutical companies invested ~7.0% of their revenues in the R&D process in 2015 and R&D investment grew by 8.6% in 2019. Thus, increasing R&D expenditure is fueling the growth of the solvent evaporation market.

The report segments global solvent evaporation market as follows:

By Type

• Rotary Evaporators
• Nitrogen Blowdown Evaporators
• Centrifugal Evaporators
• Spiral Air Flow Evaporators

By End User

• Pharmaceutical and Biopharmaceutical Industry
• Diagnostic Laboratories
• Research and Academic Institutes

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