Protein Expression Market Know the Scope and Trends

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the “Protein Expression Market”-, By Type of Protein Expression System (Algal, Cell-free, Insect, Mammalian, Prokaryotic and Yeast), Protein Expression-related Offerings (Competent Cells, Expression Vectors, Instruments, Kits and Reagents, and Protein Expression Services), Application Area (Research and Diagnostics, and Therapeutics), End-users (Academic and Research Institutes, CROs and CDMOs, Pharmaceutical / Biotechnology Companies, and Other End-users), Type of Operation (In-house and Outsourced Operations), Industry Trends, and Global Forecasts, 2024-2031 And Segment Revenue and Forecast To 2031.”

The Protein Expression Market Size is valued at USD 2.5 Bn in 2023 and is predicted to reach USD 4.6 Bn by the year 2031 at an 7.7% CAGR during the forecast period for 2024-2031.

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Protein expression refers to the biological process by which proteins are synthesized, regulated, and modified within living organisms. This process relies on a range of components, including competent cells, reagents, specialized instruments, services, and expression vectors. Among these, reagents are expected to capture the largest market share due to their extensive utilization in bio-experiments and research applications.

The protein expression market is poised for substantial growth, driven by increasing investments from governmental and non-governmental organizations in protein research, the rising prevalence of chronic diseases, and the overall expansion of the life sciences sector. Moreover, the growing demand for protein-based biologics and the increasing incidence of chronic disorders are anticipated to further accelerate market development during the forecast period.

List of Prominent Players in the Protein Expression Market:

·      Agilent Technologies

·      Ajinomoto Bio-Pharma Services

·      Aldevron

·      ARTES Biotechnology GmbH

·      Bio-Rad Laboratories

·      BIONEER CORPORATION

·      Cayman Chemical

·      Charles River Laboratories

·      CORNING INCORPORATED

·      Domainex

·      DANAHER CORPORATION

·      Eurofins CALIXAR

·      FUJIFILM IRVINE SCIENTIFIC, INC.

·      GeNext Genomics

·      GenScript Biotech

·      Lonza

·      Lucigen Corporation

·      LifeSensors Inc

·      LEADING BIOLOGY, INC.

·      Merck KGaA

·      New England Biolabs

·      Oxford Expression Technologies

·      ProMab

·      Promega

·      ProteoGenix

Market Dynamics:

Drivers:

The increasing adoption of biologics, including therapeutic proteins, monoclonal antibodies, and vaccines, for the treatment of cancer, autoimmune diseases, and chronic conditions is a key factor driving the market. Unlike traditional small-molecule drugs, biologics require advanced protein expression systems to facilitate their development and production. The rapid expansion of the biotechnology and pharmaceutical sectors, driven by advancements in drug discovery, personalized medicine, and therapeutic proteins, is further fueling demand for innovative protein expression technologies.

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Challenges:

The production of complex proteins, particularly those requiring post-translational modifications such as glycosylation, presents significant challenges. Prokaryotic expression systems, such as E. coli, often lack the capability to generate properly folded or modified proteins, necessitating the use of more sophisticated and cost-intensive platforms, such as mammalian cell-based systems, which can increase overall production costs.

Regional Trends:

North America, particularly the United States, holds the largest market share due to its well-established biotechnology and pharmaceutical industries, extensive research and development (R&D) initiatives, and substantial healthcare expenditure. The rising prevalence of chronic diseases, including cancer and autoimmune disorders, has heightened demand for therapeutic proteins such as monoclonal antibodies and vaccines.

Meanwhile, the Asia-Pacific region is experiencing the fastest growth in the protein expression market, driven by increased investments in biotechnology, expansion of pharmaceutical industries, and rising healthcare needs. The region is emerging as a key hub for outsourcing protein expression and biopharmaceutical production, owing to lower operational costs and the availability of skilled labor.

Recent Developments:

·      In June 2024, HERCULES, Calif.,Bio-Rad Laboratories, Inc. The launch of the ddSEQTM Single-Cell 3' RNA-Seq Kit and corresponding Omnition v1.1 analysis software for single-cell transcriptome and gene expression research was announced by a global leader in life science research and clinical diagnostics products.

·      In April 2023, Eurofins CALIXAR, declared the purchase of CALIXAR, a pioneer in providing the best membrane proteins for the life sciences. The purchase strengthens Eurofins Discovery and Eurofins DiscoverX®'s scientific leadership in G Protein-Coupled Receptors (GPCRs) and ion channels and provides critical capabilities in membrane protein synthesis of highly druggable targets. Gaining more knowledge in these crucial fields enhances the business's Biophysics and Biotherapeutics platforms, as well as its Integrated Drug Discovery platform, DiscoveryOneTM.

·      In March 20022, ProteoGenix, declares the release of its transient expression system, XtenCHOTM. In comparison to previous methods, the novel patented mammalian cell-based expression host produces up to ten times higher yields with less hands-on time because of its optimised metabolism and enhanced plasmid stability. The novel CHO host seeks to expedite early phase drug screening and streamline the manufacture of recombinant proteins.

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Segmentation of Protein Expression Market.

Global Protein Expression Market- By Type of Protein Expression System              

·      Algal Expression Systems

·      Cell-free Expression Systems

·      Insect Expression Systems

·      Mammalian Expression Systems

·      Prokaryotic Expression Systems

·      Yeast Expression Systems

Global Protein Expression Market – Protein Expression-related Offerings              

·      Competent Cells

·      Expression Vectors

·      Instruments

·      Kits and Reagents

·      Protein Expression Services

Global Protein Expression Market – By Application

·      Research and Diagnostics

·      Therapeutics

Global Protein Expression Market – By End user

·      Academic and Research Institutes

·      CROs and CDMOs

·      Pharmaceutical and Biotechnology Companies

·      Other End-users

·      Type of Operation     

·      In-house Operations

·      Outsourced Operations

Global Protein Expression Market – Type of Operation          

·      In-house Operations

·      Outsourced Operations

Global Protein Expression Market – By Region

North America-

·      The US

·      Canada

·      Mexico

Europe-

·      Germany

·      The UK

·      France

·      Italy

·      Spain

·      Rest of Europe

Asia-Pacific-

·      China

·      Japan

·      India

·      South Korea

·      Southeast Asia

·      Rest of Asia Pacific

Latin America-

·      Brazil

·      Argentina

·      Rest of Latin America

 Middle East & Africa-

·      GCC Countries

·      South Africa

·      Rest of the Middle East and Africa

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