Pharmaceutical Industry Today

Osteonecrosis Treatment Market Outlook, Size, Trends and Industry Report 2023-2030

Alcohol consumption and sickle cell anemia contribute to the osteonecrosis treatment market, increasing the risk of this condition. Managing alcohol use and addressing sickle cell anemia are essential in treatment and prevention, highlighting the importance of these factors.
Published 07 November 2023

Osteonecrosis Treatment Market Size

Global Osteonecrosis Treatment Market reached US$ YY billion in 2022 and is expected to reach US$ YY billion by 2030 growing with a high CAGR during the forecast period 2023-2030.  

Osteonecrosis, alternatively known as avascular necrosis or aseptic necrosis, is a medical condition characterized by the death or necrosis of bone tissue resulting from insufficient blood flow. When blood circulation to a specific bone is disrupted or restricted, the bone cells deteriorate and eventually die. 

The global market for osteonecrosis treatment comprises a range of therapeutic options, including Nonsteroidal Anti-Inflammatory Drugs (NSAIDs), cholesterol-lowering medications, and blood thinners. This market is primarily influenced by factors such as the rising prevalence of osteonecrosis, the excessive use of steroids, traumatic injuries, a growing elderly population, and advancements in technology. 

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Market Driver 

The increasing consumption of alcohol is a significant driver of the osteonecrosis treatment market. Excessive alcohol use is a known risk factor for osteonecrosis as it impairs blood circulation, particularly in weight-bearing joints like the hip and knee, leading to reduced blood flow in these areas. 

As per a National Library of Medicine article from 2023, alcohol consumption is a major risk factor for osteonecrosis, affecting a significant proportion of people with the condition, with estimates ranging from 20% to 45%. Furthermore, the prevalence of aseptic necrosis (another term for osteonecrosis) in habitual drinkers was reported to be as high as 5.3%. 

In addition to alcohol consumption, the rising prevalence of sickle cell anemia, a genetic blood disease characterized by malformed, sickle-shaped red blood cells, can also contribute to osteonecrosis. The abnormal red blood cells in sickle cell anemia can block small blood vessels, restricting blood supply to various organs, including bones. This reduced blood flow leads to ischemia, which causes bone tissue cells to die due to a lack of oxygen and nutrients. 

According to another National Library of Medicine article from 2022, the incidence of osteonecrosis of the femoral head has been reported to be as high as 22% in patients with sickle cell disease, and in some cases, it can be as high as 50%. These factors underscore the importance of addressing alcohol consumption and managing conditions like sickle cell anemia in the context of osteonecrosis treatment and prevention. 

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Market Segmentation 

By Type 

  • Traumatic 
  • Non-traumatic  

By Treatment Type 

  • Medication 
  • Surgery  

By Sales Channel 

  • End User* 
  • Distribution Channel 

Market Key Players 

Major players are Novartis AG, Pfizer Inc, Teva Pharmaceutical Industries Ltd, Mylan N.V., Zimmer Biomet, Stryker, Merck & Co.,Inc, Horizon Therapeutics plc, Biotek, and Upsher-Smith Laboratories, LLC. 

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