Organoids Market projected to reach US$ 3,420.40 million by 2027 - Hubrecht Organoid Technology, Definigen, 3Dnamics, Organoid Therapeutics, PeproTech

According to our new research study on “Organoids Market to 2027 – Global Analysis and Forecast – by Type, Application, and Source,” the organoids market was valued at US$ 689.47 million in 2019 and is projected to reach US$ 3,420.40 million by 2027; it is expected to grow at a CAGR of 22.1% during 2020–2027. The growth of the market is attributed to increasing demand for tumor modelling and biobanking, escalating adoption of personalized drugs, and growing focus on developing alternatives for animal testing models. However, issues related to the incorporation of organoids into existing workflows and dearth of skilled professionals hinder the growth of the market. `

In 2019, North America dominated the global organoids market. The market growth in the region is credited to the rise in the implementation of organoid-based research models in the biotechnology sector in US and Canada. These novel technologies have helped the researchers to overcome limitations faced by 2D cell culture platforms as 3D spheroids offer a microenvironment that can mimic the properties of human tissue structures. The market growth in Canada and Mexico is attributed to the presence of international market players, increasing adoption of advanced technologies, and existence of supportive government regulations. Based on type, the organoids market is segmented into stomach, intestine, liver, pancreas, lung, brain, kidney, and lung. The intestine segment accounted for more than 23.31% of the market in 2019. On the basis of application, the organoids market is segmented into developmental biology disease, pathology of infectious disease, regenerative medicine, drug toxicity and efficacy testing, drug discovery and personalized medicine, and others. The developmental biology disease segment is expected to held the largest share of the market in 2019 owing to its consideration as primary investigative research tool of the human developmental biology. Further, the pluripotent stem cells segment accounted for a larger share in the organoids market, by source, in 2019.

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Organoids Market: Competition Landscape and Key Developments

STEMCELL Technologies, Inc, Cellesce Ltd., Hubrecht Organoid Technology, Definigen, 3Dnamics, Inc., Organoid Therapeutics, PeproTech, Inc., Thermo Fisher Scientific, Corning Incorporated (Life Sciences) and Merck KGgA. are among the key companies operating in the global organoids market. Leading players are focusing on the expansion and diversification of their market presence, and acquisition of new customer base, thereby tapping prevailing business opportunities.

Increasing Use of Personalized Drugs Fuels Organoids Market Growth

Personalized medicine is a flourishing area of therapeutics that relies on specific drug delivery and dosing. As per a study published by PMC, personalized medicines accounted for only 5% of the new FDA-approved molecular entities in 2005, whereas they accounted for more than 25% in 2016. Additionally, 42% of all compounds and 73% of oncology compounds in the pipeline have the potential to be prescribed as personalized medicines. Biopharmaceutical companies have nearly doubled their R&D investments in personalized drugs in the past five years, and they are further likely to increase by 33% in the next five years. Biopharmaceutical researchers also predict a 69% increase in the development of personalized medicines over the coming five years.

The implementation of organoids to create personalized drug therapies is providing exciting opportunities for improving patient care. Recent research has highlighted that more than 50% of consumers express an interest in purchasing customized products or services. Since the release of the Precision Medicine Initiative  in the US in 2015, pharmaceutical researchers have been pursuing the development of more tailored treatments for making medicines safer and more effective.

Personalized cancer therapy involves using personalized tumor models with similar characteristics to the original tumors, which may result in accurate predictions of drug responses in patients. One of the key advantages of tumor organoid models involve the conservation of molecular and cellular composition of the original tumor, which highlights the tremendous potential of tumor organoids in personalized cancer therapy, particularly in preclinical drug screening and predicting patient responses to selected treatment regimens.

Organoids Market: Segmental Overview

In terms of type, the kidney organoids segment is anticipated to register the highest CAGR in the organoids market during the forecast period. Kidney organoids, derived from human pluripotent stem cells, have the potential to assist the drug development process. An international team of researchers—led by Nanyang Technological University Singapore (NTU Singapore)—has grown “miniature kidneys” in laboratory, which could be used to better understand the mechanism of development of renal diseases in individual patients. The mini kidneys, i.e., kidney organoids, were grown in vitro from skin cells derived from a single patient who had polycystic kidney disease, one of the most common inherited causes of kidney failure in adults. In terms of application, the developmental biology disease segment accounted for more than 29% share in global organoids market in 2019. In terms of source, the market for the pluripotent stem cells segment is anticipated to grow at a higher CAGR during the forecast period.

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