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Lamellar Ichthyosis Market Growth Anticipated by 2032 | Major Players: Krystal Biotech, Timber Pharmaceuticals
In the market landscape of Lamellar Ichthyosis, an impressive surge is expected during the study period spanning 2019 to 2032, according to latest report titled “Lamellar Ichthyosis Market Insights, Epidemiology and Market Forecast, 2032” from DelveInsight.
The dynamics of the Lamellar Ichthyosis market is anticipated to change in the coming years owing to the rise in numbers of company’s taking interest in development of drugs for Lamellar Ichthyosis, improvement in the diagnosis, expected launch of emerging therapies during the forecast period.
The Lamellar Ichthyosis market report sheds light on Lamellar Ichthyosis current treatment practices, upcoming drugs in the Lamellar Ichthyosis pipeline, market shares of individual therapies, and the anticipated trajectory of the Lamellar Ichthyosis market size from 2019 to 2032 across the 7MM (the United States, the EU-4 comprising Italy, Spain, France, and Germany, the United Kingdom, and Japan).
Driving Forces Behind the Lamellar Ichthyosis Market Growth
DelveInsight’s analysts estimate that the market is expected to show positive growth, mainly attributed to increasing prevalence, improved diagnosis, and the anticipated launch of novel therapies during the forecast period.
Discover the Anticipated Evolution and Growth of the Market @ Lamellar Ichthyosis Therapeutics Market Forecast
Therapeutic Advancements and Emerging Treatments:
- Lamellar Ichthyosis Clinical Trial Progression: The market is set to experience significant growth, driven by the progression of emerging therapies expected for launch between 2023 and 2032. Pioneering companies, including Krystal Biotech, Timber Pharmaceuticals, and others, are actively engaged in developing novel drugs for potential market entry.
- Lamellar Ichthyosis Innovative Therapies: Ongoing research and development activities are fostering the introduction of innovative therapies designed to address the signs and symptoms of Lamellar Ichthyosis. Therapies such as TMB-001, KB105, and others are driving the Lamellar Ichthyosis market.
Lamellar Ichthyosis Market Dynamics
The market of Lamellar Ichthyosis is largely dependent on off-label therapies due to a lack of treatment options. Lamellar Ichthyosis highly impacts patients' quality of life, and this is a great medical unmet need, as there are no effective drug treatments available in the 7MM. To overcome this major unmet need, companies like Timber Pharmaceuticals, Galderma/Mayne Pharma, and Krystal Biotech working towards the development of a better treatment approach for Lamellar Ichthyosis patients. Expected entry of their investigational products or treatment options would offer considerable hope to sufferers of Lamellar Ichthyosis and to their families.
Lamellar Ichthyosis Treatment Market
“Currently, there is no approved therapy for the treatment of Lamellar Ichthyosis, however, the off-label therapies like retinoids, emollients, and keratolytics are available for symptomatic treatment like removal of scales. The general treatment course is aimed at controlling symptoms with exfoliating creams and ointments application being found to be crucial.”
Lamellar Ichthyosis Market Report
Geography Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
Study Period: 2019-2032
Lamellar Ichthyosis Market Size: USD XX million in 2032
Key Lamellar Ichthyosis Companies: Krystal Biotech, Timber Pharmaceuticals, and others.
Leading Lamellar Ichthyosis Companies and Emerging Drugs: Pioneering companies such as Krystal Biotech, Timber Pharmaceuticals, among others, are actively developing novel drugs for potential entry into the Lamellar Ichthyosis market.
Lamellar Ichthyosis Therapeutic Landscape: Key therapies identified for Lamellar Ichthyosis treatment include TMB-001, KB105, and more.
Lamellar Ichthyosis Overview:
Lamellar Ichthyosis is an uncommon genetic condition where skin cells are produced at a normal rate but fail to separate properly at the surface of the outer skin layer. Consequently, they do not shed as efficiently as they should, resulting in the formation of scales.
Infants affected by Lamellar Ichthyosis are born enclosed in a thick, transparent membrane known as a collodion baby. Within about two weeks, these infants develop large, thick, brownish scales with minimal redness. Furthermore, Lamellar Ichthyosis can lead to additional features such as crumpled ears, hair loss (alopecia), turned-out lips (eclabium), and an outward turning of the eyelids (ectropion).
This condition primarily stems from mutations in several genes, notably TGM1, ABCA12, CYP4F22, NIPAL4, and others like LIPN and ALOX12B. However, a significant majority of cases (~90%) are due to mutations specifically in the TGM1 gene.
Lamellar Ichthyosis, a rare genetic disorder, presents a variety of symptoms primarily affecting the skin. These symptoms may include:
Scaly skin: Thick, plate-like scales cover the skin, giving it a rough, scaly appearance. These scales might be brownish or have a dark hue.
Collodion membrane: Infants affected by Lamellar Ichthyosis are typically born encased in a tight, transparent membrane known as a collodion membrane or collodion baby. This membrane eventually sheds, revealing the scaly skin.
Minimal redness (erythema): Though scales develop, there is usually minimal redness associated with the condition.
Associated facial features: Other features might include crumpled ears, hair loss (alopecia), outwardly turned lips (eclabium), and eyelids that turn outward (ectropion).
Key Facts Lamellar Ichthyosis Market Report:
- Key players such as Krystal Biotech, Timber Pharmaceuticals are investigating its candidates for Lamellar Ichthyosis.
- Among the 7MM, US accounts for the largest market size of Lamellar Ichthyosis, in comparison to EU4and the UK (United Kingdom, Spain, Italy, France, Spain) and Japan. The market size shall increase during the forecast period (2019‒2032), owing to the launch of upcoming therapies.
- The market Size of Lamellar Ichthyosis (LI) in the United States, EU5 (Germany, Spain, Italy, France and the United Kingdom), and Japan was found to be around USD XX million in 2019.
- The Lamellar Ichthyosis market heavily relies on using medications for purposes other than their originally intended use due to a lack of specific treatment options. The condition significantly affects the quality of life for those affected, presenting a substantial medical gap as there are no effective approved drug therapies available across various global markets. In response to this significant medical need, companies such as Timber Pharmaceuticals, Galderma/Mayne Pharma, and Krystal Biotech are actively engaged in developing improved treatment strategies for individuals with Lamellar Ichthyosis. The anticipated introduction of their investigational products or potential treatment alternatives holds significant promise for individuals and families affected by Lamellar Ichthyosis, offering a renewed sense of hope.
Lamellar Ichthyosis Epidemiology Segmentation:
“Lamellar ichthyosis affects approximately 1 in 200,000 in the United States. The most frequently reported prevalence is 1 in 200,000 – 300,000. Consanguinity of parents is present in about 8% of cases. Premature birth occurs in 25% of individuals and 51% of siblings are affected. LI is most commonly inherited as an autosomal recessive trait, but autosomal dominant transmission has been observed.”
- According to DelveInsight’s estimates, the genetic mutation-specific cases of Lamellar Ichthyosis in the 7MM for TGM1, ABCA12, CYP4F22, NIPAL4, Others (i.e., LIPN, ALOX12B) were found to be 1,817, 20, 40, 81, and 61 cases respectively, in the year 2017. These cases are estimated to increase in upcoming years.
- According to DelveInsight’s estimates, the US accounted for the highest number of patients with Lamellar Ichthyosis (LI) among the 7MM.
- According to Foundation For Ichthyosis and Related Skin Types, lamellar ichthyosis has an equal incidence in males and females and is estimated to occur approximately 1 in 300,000 live births in the United States.
The Lamellar Ichthyosis market report proffers epidemiological analysis for the study period 2019–2032 in the 7MM segmented into:
• Total Prevalence of Lamellar Ichthyosis
• Prevalent Cases of Lamellar Ichthyosis by severity
• Gender-specific Prevalence of Lamellar Ichthyosis
• Type-specific Prevalence of Lamellar Ichthyosis
• Age-specific Prevalence of Lamellar Ichthyosis
• Diagnosed Cases of Lamellar Ichthyosis
DelveInsight's comprehensive report provides a thorough exploration of the Lamellar Ichthyosis market, covering key Lamellar Ichthyosis players, emerging Lamellar Ichthyosis therapies, treatment dynamics, and market challenges.
For in-depth insights, access the full report @ Lamellar Ichthyosis Market Outlook 2032
DelveInsight's report offers comprehensive insights, market analysis, and forecasts aiding leading companies in strategic decision-making for the Lamellar Ichthyosis market landscape.
- Gain Competitive Edge in Indication Market : Understand the current landscape of the Lamellar Ichthyosis market, including the competitive environment, key companies developing drugs for Lamellar Ichthyosis , and their strategies. By analyzing market dynamics, treatment approaches, and emerging therapies, stakeholders can identify opportunities to position themselves effectively, gaining a competitive edge over others.
- Identify Market Gaps and indication market opportunities : Analyzing epidemiological trends, country wise patient journeys and existing tretment practices can helps in identifying gaps and opportunities within the Lamellar Ichthyosis market. This involves recognizing areas where current treatments may be insufficient or where there is an unmet need. The report is curated by taking account of various KOLs dealing with Lamellar Ichthyosis. Identifying these gaps allows stakeholders to explore new therapeutic avenues, potentially leading to the development of novel treatments that address specific market needs and price their emerging products strategically to gain a competitive edge.
- Strategic decision making : Armed with insights from epidemiological and market forecasts, stakeholders can make informed and strategic decisions. This may involve deciding on research and development investments, portfolio expansion, pricing - reimbursement strategies, partnerships, or other strategic moves. Understanding the market dynamics enables stakeholders to align their goals with the prevailing trends and future projections.
- Plan RoadMap to Success : Through this report the leading companies can set short-term and long-term goals, define strategies for market penetration, and outline steps for product development or market expansion. A well-informed roadmap ensures that stakeholders navigate the complexities of the Lamellar Ichthyosis market with clarity and purpose.
Related Reports:
Lamellar Ichthyosis Epidemiology Forecast
Lamellar Ichthyosis Epidemiology Forecast report delivers an in-depth understanding of the Lamellar Ichthyosis, historical and forecasted epidemiology in the United States, the EU5 (Germany, Spain, Italy, France, and the United Kingdom), and Japan.
Lamellar Ichthyosis Pipeline Insight
Lamellar Ichthyosis Pipeline Insight report provides comprehensive insights about companies and pipeline drugs in the Lamellar Ichthyosis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type.
Healthcare Consulting and Market Research Services by DelveInsight
Discover how DelveInsight’s comprehensive analysis and proactive strategies facilitated a US-based pharmaceutical client’s triumphant entry into the European biosimilar landscape. Download Pharma Go-to-Market Case Study.
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