Global Organ Transplant Immunosuppressant Drugs Market to Decline at -5.0% CAGR till 2023 due to Demand and Supply Imbalance

The global organ transplant immunosuppressant drugs market is restrained by several factors. Factors such as the high cost of procedure and inadequate insurance coverage are projected to suppress the global organ transplant immunosuppressant drugs market in the coming few years. In addition to this, the advent of stem cells and lack of donor organs will also constrain the global organ transplant immunosuppressant drugs market in the foreseeable future. Nevertheless, the global market for organ transplant immunosuppressant drugs will benefit from the growing incidence of chronic diseases resulting in organ failure and disabilities.
 
By drug class, the global organ transplant immunosuppressant drugs market is divided into steroids, antibodies, mTOR inhibitors, antiproliferative agents, calcineurin inhibitors. The global organ transplant immunosuppressant drugs market was led by the calcineurin inhibitors sector in 2014. This sector was estimated at US$2.3 bn in 2014. The majority of kidney transplant recipients are prescribed tacrolimus to maintain immunosuppressive regimen due to its higher potency and lower rejection nephrotoxicity as compared to cyclosporine. 

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Corticosteroids are given to patients in high dosages in the initial stages of organ transplantation. Some of the most common corticosteroids used during the process of organ transplantation include methylprednisolone, prednisolone, and oral prednisone.
 
On the basis of organ, the global organ transplant immunosuppressant drugs market is segmented into lungs, heart, liver, bone marrow, kidney, and others. In 2014, the kidney transplant segment held more than 50% of the global organ transplant immunosuppressant drugs market. The market segment of kidney transplants is expected to continue its dominance throughout the forecast period due to the high availability of kidneys from live and deceased donors in comparison to other organs.

Geography-wise, the global organ transplant immunosuppressant drugs market is segmented into Latin America, Asia Pacific, Europe, North America, and Rest of the World. The WHO states that in 2013, the U.S. was the most lucrative country for organ transplantation. The North American region leads the global organ transplant immunosuppressant drugs market due to technological improvements, enhanced surgical techniques, enhanced immunosuppressive drugs, and rising success rate of organ transfer procedures.

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The overall market for organ transplant immunosuppressant drugs will decline in the forecast period due to the imbalance in demand and supply of donor organs. It is also projected that the need for continuous follow-up and infection risk after surgery could restrain the uptake of immunosuppressant drugs.
 
Players in the global organ transplant immunosuppressant drugs market will benefit from the emergence of newer medication options. Some of the key players operating in this market are Astellas Pharma, Allergan, AbbVie, Novartis, Sanofi, Bristol-Myers Squibb Company, and Pfizer.
 
Key Segments of the Global Organ Transplant Immunosuppressant Drugs Market

Global Organ Transplant Immunosuppressant Drugs, by Drug Class

• Calcineurin Inhibitors
• Tacrolimus
• Cyclosporine
• Antiproliferative Agents
• Mycophenolate Mofetil
• Mycophenolate Sodium
• Azathioprine
• mTOR Inhibitors
• Sirolimus
• Everolimus
• Antibodies
• Antithymocyte Globulin
• Muromonab-CD3
• Alemtuzumab
• Rituximab
• Daclizumab
• Basiliximab
• Belatacept
• Eculizumab
• Steroids 

Global Organ Transplant Immunosuppressant Drugs, by Transplant

• Kidney
• Bone Marrow
• Liver
• Heart
• Lungs
• Others (Intestinal and Multi-visceral Organs)

Global Organ Transplant Immunosuppressant Drugs, by Geography

• North America
• U.S.
• Canada
• Europe
• U.K.
• Germany
• Rest of Europe
• Asia Pacific
• Australia
• Japan
• Rest of Asia Pacific
• Latin America
• Brazil
• Rest of Latin America
• Rest of the World

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