Global Hypoparathyroidism Market is Set to Evolve Over the Next 10 Years - BIS Research

What is Hypoparathyroidism? 

Hypoparathyroidism is a rare disorder in which the four parathyroid glands produce too little parathyroid hormone (PTH), resulting in low blood calcium (hypocalcemia) and high phosphorus. Common causes include accidental removal or injury during thyroid surgery, autoimmune attacks on the glands, genetic mutations, or radiation exposure. Symptoms range from muscle cramps and tingling to fatigue and, in severe cases, cardiac or neurological complications. 

What is the Current Market Outlook for Hypoparathyroidism? 

The global hypoparathyroidism market is in its growth phase, driven by rising diagnosis rates, greater awareness, and expanding treatment access. From 2025 to 2035, demand for therapies is expected to grow significantly, supported by favorable regulatory policies and increased healthcare access in emerging markets. 

What is the key Innovation & Trends in Hypoparathyroidism Market 

Key trends include the rise of novel parathyroid hormone therapies, focus on personalized medicine, and robust R&D investment in rare disease treatments. An expanding clinical pipeline and improved diagnostics fueling therapeutic innovation and market expansion. 

What is the Major Development of the Hypoparathyroidism Market? 

• Feb 2025 – TGA Approval: YORVIPATH by Specialised Therapeutics approved in Australia for chronic hypoparathyroidism. 

• Aug 2024 – FDA Approval: Once-daily parathyroid hormone prodrug approved for adult treatment. 

• Jul 2024 – Strategic Partnership: Pendopharm partners with Ascendis Pharma to distribute TransCon PTH in Canada. 

How Does This Report Help Organizations Drive Strategic Growth? 

•  Strategic Insights: Helps stakeholders identify growth opportunities through market trends, drivers, and competitive benchmarking. 
• Innovation Tracking: Highlights product pipelines and key advancements by leading players. 
• Investment Support: Informs decision-making with regulatory updates, partnership analysis, and emerging technologies. 
• Market Positioning: Enables businesses to evaluate their standing and develop effective go-to-market strategies. 

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What Are the Key Demand Drivers, Challenges, and Growth Opportunities in the Hypoparathyroidism Market? 

Drivers: 

• Increasing prevalence of hypoparathyroidism 

• Rising awareness and advancements in diagnostic technologies 

Challenges: 

• High treatment costs impacting accessibility and adoption 

Opportunities: 

• Growing R&D in novel parathyroid hormone therapies 

• Expanding healthcare access in emerging markets 

• Supportive regulatory environment for rare disease treatments 

What Is the Competitive Landscape in Hypoparathyroidism Market? 

Key Players 

• Ascendis Pharma 

• AstraZeneca 

• Bridgebio 

• Entera Bio Ltd. 

• MBX Biosciences, Inc. 

• Specialised Therapeutics 

• Visen Pharmaceuticals (Shanghai) Co., Ltd. 

Strategic Inititives 

• Shift to parathyroid hormone (PTH) analogs from traditional supplements for better calcium-phosphorus regulation. 

• Orphan drug policies accelerating novel treatment development. 

• Digital tools like apps and remote monitoring enhance personalized care. 

Here Are Some Case Studies and Success Stories in the Hypoparathyroidism Market 

The introduction of palopegteriparatide, a recombinant human PTH therapy, marked a significant advancement in treatment. Despite its initial success, safety concerns led to market withdrawal in some regions, underscoring the need for next-generation therapies with improved safety profiles. 

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