Health & Safety Industry Today

Protein Design and Engineering Market Current Scenario with Future Aspect Analysis

North America leads the market, while Asia-Pacific shows the fastest growth. Key challenges include high R&D costs and complex regulatory requirements.
Published 11 November 2025

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the " “Global Protein Design and Engineering Market by Type of Protein Engineering Approach Used (Rational Designing, Directed Evolution, Semi-Rational Designing) Trends, Industry Competition Analysis, Revenue and Forecast To 2034."

According to the latest research, the Global Protein Design and Engineering Market Size is valued at USD 6.4 Billion in 2024 and is predicted to reach USD 25.1 Billion by the year 2034 at a 15.0 % CAGR during the forecast period for 2025-2034.

 

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The industrial and healthcare sectors have witnessed substantial growth in protein engineering, a field dedicated to modifying and optimizing protein structures to create novel proteins with tailored functions. This technology finds applications across diverse industries, including pharmaceuticals, food production, nanobiotechnology, and environmental science.

The global Protein Design and Engineering market is being driven by several key factors, including the rising prevalence of chronic, infectious, and protein-deficiency-related diseases, rapid technological advancements, and increasing demand for personalized medicine. Furthermore, growing government investments in research and development (R&D), the presence of robust healthcare infrastructure, and the advancement of bioinformatics tools and databases are supporting the expansion of the market.

Furthermore, the biopharmaceutical sector is increasingly utilizing protein design techniques to enhance drug development, which is expected to drive substantial market expansion in the coming years. As chronic disease prevalence continues to rise, there is a growing need for innovative treatments and medications. To enhance the specificity and effectiveness of therapeutic proteins and drugs, biopharmaceutical companies are leveraging advanced protein design and engineering methodologies. This trend is expected to create new business opportunities within the industry. Notably, in June 2019, Amgen (U.S.) partnered with the University of Washington’s Institute for Protein Design (IPD) to explore new technologies and develop innovative protein-engineering strategies for drug discovery.


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Key market players operating in the protein design and engineering market include ATUM (US), Creative BioMart (US), Creative Biostructure (US), Creative Enzymes (US), Absolute Antibody (UK), EUCODIS Bioscience (Austria), Biomatter Designs (Lithuania), Fusion Antibodies (UK), Innovagen (Sweden), ZYMVOL (Spain), Averring Biotech, EnzymeWorks (China), GeNext Genomics (India), Quantumzyme (India), among others.

Key developments in the market:

·      In August 2021, ATUM (US), a pioneer in bioengineering solutions, announced that the United States Patent and Trademark Office (USPTO) had issued patent numbers 11,060,098, 11,060,109 11,060,086, which expand the scope of the Leap-In Transposase platform, the company's innovative transposon-based tool for genome engineering.

·      In January 2021, Biomatter Designs (Lithuania), pioneers the technologies for generative protein design, raised €500k in seed funding led by Practica Capital to develop the company’s protein design technology and product pipeline.

·      In January 2021, Zymvol Biomodeling (Spain) collaborated with Aminoverse, a biotech company specializing in enzyme discovery and design, to develop custom-made alcohol dehydrogenases, an enzyme most commonly used in the flavors and fragrances and the fine chemicals industry.


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Market Segments

Global Protein Design and Engineering Market, by Type of Protein Engineering Approach Used, 2015-2034 (Value US$ Bn)

·      Rational Designing

·      Directed Evolution

·      Semi-Rational Designing

Global Protein Design and Engineering Market, by Protein Types, 2025-2034 (Value US$ Bn)

·      Antibodies

·      Peptides

·      Enzymes

·      Vaccines

·      Others

Global Protein Design and Engineering Market, by Type of Application, 2025-2034 (Value US$ Mn)

·      Therapeutics

·      Diagnostics

Global Protein Design and Engineering Market, by End-Users, 2025-2034 (Value US$ Bn)

·      Pharma / Biotech Firms

·      CROs and Research

·      Academic Institutes

Global Protein Design and Engineering Market, by Region, 2025-2034 (Value US$ Bn)

·      North America

·      Europe

·      Asia Pacific

·      Latin America

·      Middle East & Africa

North America Protein Design and Engineering Market, by Country, 2025-2034 (Value US$ Bn)

·      U.S.

·      Canada

Europe Protein Design and Engineering Market, by Country, 2025-2034 (Value US$ Bn)

·      Germany

·      France

·      Italy

·      Spain

·      Russia

·      Rest of Europe

Asia Pacific Protein Design and Engineering Market, by Country, 2025-2034 (Value US$ Bn)

·      India

·      China

·      Japan

·      South Korea

·      Australia & New Zealand

Latin America Protein Design and Engineering Market, by Country, 2025-2034 (Value US$ Bn)

·      Brazil

·      Mexico

·      Rest of Latin America

The Middle East & Africa Protein Design and Engineering Market, by Country, 2025-2034 (Value US$ Bn)

·      South Africa

·      GCC Countries

·      Rest of the Middle East & Africa

 

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