Non-covid mRNA Vaccine and Therapeutics Market Report- Expansive Coverage on the Profit Sources

InsightAce Analytic Pvt. Ltd. announces the release of a market assessment report on the "Global Non-covid mRNA Vaccine and Therapeutics Market Size, Share & Trends Analysis Report By Product Type (mRNA Therapeutic, mRNA Vaccines), By Therapeutic Area (Infectious Diseases, Oncological Disorders, Other Disorders), By Route of Administration (Intravenous, Intramuscular, Intranasal, Others)- Market Outlook and Industry Analysis 2031"

The Global Non-covid mRNA Vaccine and Therapeutics Market is valued at US$ 370.0 Mn in 2024, and it is expected to reach US$ 1,684.80 Mn by 2031, with a CAGR of 24.20% during the forecast period of 2024-2031.

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Advancements in mRNA technology have accelerated the development of medical therapeutics and vaccines, positioning the non-COVID mRNA vaccine and therapeutics market for significant expansion. This innovative approach utilizes synthetic mRNA to direct cells to produce specific proteins that can prevent or treat a wide range of diseases, including infectious illnesses, cancers, and certain genetic disorders.

The applications of non-COVID mRNA therapeutics are vast and transformative. mRNA vaccines are currently in development for infectious diseases such as influenza, HIV, and Zika, aiming to elicit robust immune responses. In oncology, personalized mRNA vaccines encoding tumor-specific antigens are being designed to activate the immune system to recognize and destroy cancer cells based on individual tumor profiles.

List of Prominent Players in the Non-covid mRNA Vaccine and Therapeutics Market:

·      CureVac

·      Anima Biotech

·      Arcturus Therapeutics

·      BioNTech (Pfizer)

·      eFFECTOR Therapeutics, Inc.

·      eTheRNA

·      Ethris (AstraZeneca)

·      H3 Biomedicine Inc. (Eisai Inc.)

·      In-Cell-Art

·      Ionis Pharmaceuticals, Inc.

·      Kernal Biologics

·      Moderna

·      RNAimmune (Sirnaomics)

·      Silence Therapeutics

Market Dynamics:

Drivers:

The growth of the non-COVID mRNA vaccines and therapeutics market is primarily driven by advancements in technology that enhance stability, delivery, and efficacy—particularly through innovations such as lipid nanoparticles (LNPs). The vast potential applications of mRNA therapeutics, spanning infectious disease prevention, personalized cancer therapies, and genetic disorder treatments, continue to expand the market scope. The scalability and rapid development capabilities of mRNA technology, successfully demonstrated during the COVID-19 pandemic, have established it as a reliable platform for large-scale production. 

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Challenges:

Despite its rapid progress, the market faces several operational and technical challenges. Fragmented production processes involving multiple vendors often result in inefficiencies and production delays, particularly affecting smaller firms with limited resources. The limited availability of GMP-grade raw materials poses additional constraints, leading to manufacturing bottlenecks. Moreover, the intricate nature of mRNA production—especially the need for high-purity, contamination-free synthesis—adds further complexity, increasing production costs and extending timelines.

Regional Trends:

North America leads the non-COVID mRNA vaccine and therapeutics market, supported by a robust research and development infrastructure, prominent pharmaceutical and biotechnology companies, and globally recognized academic institutions. This well-established ecosystem fosters innovation, strategic collaborations, and sustained investment. For example, Moderna’s mRNA vaccine, mRESVIA, recently received U.S. FDA approval for preventing severe RSV-related respiratory illness in adults aged 60 and above, underscoring the region’s leadership in mRNA technology. Additionally, favorable regulatory frameworks and strong public–private partnerships continue to accelerate clinical advancements and the commercialization of novel mRNA-based therapies.

Recent Developments:

·      In Jan 2023, Moderna, Inc. announced a definitive agreement to acquire OriCiro for $85 million. This acquisition provides Moderna with advanced tools for cell-free synthesis and amplification of plasmid DNA, a crucial component in the mRNA manufacturing process.

·      In Aug 2021, Sanofi entered into a definitive agreement to acquire Translate Bio, a clinical-stage mRNA therapeutics company, for $38.00 per share in cash, totaling approximately $3.2 billion. Both companies' Boards of Directors have unanimously approved the transaction, aiming to accelerate Sanofi's development of mRNA-based therapeutics and vaccines.

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Segmentation of Non-covid mRNA Vaccine and Therapeutics Market-

Non-covid mRNA Vaccine and Therapeutics Market- By Product Type

·      mRNA Therapeutic

·      mRNA Vaccines

Non-covid mRNA Vaccine and Therapeutics Market- By Therapeutic Area

·      Infectious Diseases

o  Influenza

o  Respiratory Syncytial Virus (RSV)

o  Cytomegalovirus

o  Others

·      Oncological Disorders

·      Other Disorders

Non-covid mRNA Vaccine and Therapeutics Market- By Route of Administration

·      Intravenous

·      Intramuscular

·      Intranasal

·      Others

Non-covid mRNA Vaccine and Therapeutics Market- By Region

North America-

·      The US

·      Canada

·      Mexico

Europe-

·      Germany

·      The UK

·      France

·      Italy

·      Spain

·      Rest of Europe

Asia-Pacific-

·      China

·      Japan

·      India

·      South Korea

·      South East Asia

·      Rest of Asia Pacific

Latin America-

·      Brazil

·      Argentina

·      Rest of Latin America

 Middle East & Africa-

·      GCC Countries

·      South Africa

·      Rest of Middle East and Africa

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