Health & Safety Industry Today

Necrotizing Enterocolitis (NEC) Market to Witness Robust Growth – BIS Research

The global necrotizing enterocolitis (NEC) market is on a promising trajectory, with BIS Research forecasting steady expansion over the forecast period. Growth is fueled by increasing cases of preterm and low-birth-weight births, continuous improvement in neonatal intensive care unit (NICU) technologies, and the adoption of advanced nutritional and microbiome-based solutions for the prevention and treatment of NEC in newborns.
Published 13 October 2025

What Is Necrotizing Enterocolitis (NEC)? 

Necrotizing enterocolitis is a critical gastrointestinal disorder that primarily affects premature or critically ill infants, particularly those with very low birth weight. The condition is characterized by inflammation and injury of the intestinal lining, which can lead to tissue death and, in severe instances, perforation of the intestine. Because NEC can progress rapidly, early diagnosis and intervention are vital. Treatments range from supportive care and antibiotic therapy to surgical procedures for advanced cases. 

What Is the Market Outlook? 

Technology Growth: 

Emergence of AI-powered imaging and predictive analytics tools for earlier, more accurate detection of NEC; introduction of next-generation live biotherapeutic products and microbiome modulators for tailored prevention and therapy. 

Expanding Clinical Applications: 

Broader adoption of human milk-based nutritional products, targeted probiotics, and advanced diagnostic imaging in neonatal care settings. 

Commercialization Push: 

Key industry players and healthcare providers are actively investing in innovative nutritional solutions, microbiome-targeted therapies, and AI-driven diagnostic platforms to improve early detection, optimize outcomes, and reduce risks. 

How Fast Is the Market Growing? 

The NEC market is anticipated to grow steadily in the coming years, supported by increasing demand for preventive and therapeutic solutions in neonatal care, advancements in NICU technology, and greater accessibility in emerging healthcare markets. 

How Will This Report Help You? 

Planning to Enter the Market? 

Explore opportunities in neonatal nutrition, microbiome-focused therapies, and diagnostic tools for premature and critically ill infants. 

Analyzing the Competitive Landscape? 

Examine strategies employed by healthcare and biotechnology leaders in the fields of human milk-based products, precision diagnostics, and live biotherapeutics. 

Seeking R&D Insights? 

Monitor developments in AI-enabled risk prediction, biomarker-based diagnostics, microbiome modulation, and immunotherapeutic approaches. 

Interested in Regional Market Trends? 

Gain insights into regulatory frameworks, adoption rates, and government initiatives supporting neonatal health across key regions. 

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What Technologies Are Transforming the Market? 


  • AI-powered imaging and predictive analytics 
  • Live biotherapeutic products, including targeted probiotics and microbiome modulators 
  • Human milk-based nutritional formulas 
  • Biomarker-driven diagnostic tools 
  • Precision feeding devices and advanced NICU monitoring systems 


What’s Driving Demand, Opportunities, and Barriers? 

Demand Drivers 

  • Rising number of preterm and low-birth-weight births 
  • Increased adoption of specialized nutrition and microbiome-based products 
  • Ongoing advancements in NICU technologies and diagnostic tools 

Opportunities 

  • Expansion of neonatal care infrastructure in emerging economies 
  • Increased research and development in immunotherapy and microbiome modulation 
  • Growing use of AI and digital health for predictive and personalized care 

Challenges 

  • Continued high mortality and morbidity rates despite advancements 
  • Lack of definitive biomarkers leading to delayed diagnosis 
  • Legal and regulatory challenges concerning infant formula safety 


Market Segmentation 

By Treatment Type 

  • Medical Management 
  • Antibiotic Therapy 
  • Probiotics & Prebiotics 
  • Others 
  • Surgical Intervention 
  • Peritoneal Drainage 
  • Laparotomy & Resection 
  • Stoma Formation 
  • Adjunctive & Supportive Therapies 
  • Immunotherapies 
  • Growth Factors & Cytoprotective Agents 

By Diagnosis 

  • Imaging Techniques 
  • Abdominal X-Ray 
  • Abdominal Ultrasound (AUS) 
  • Doppler Ultrasound 
  • Laboratory Tests 
  • Complete Blood Count (CBC) 
  • C-Reactive Protein (CRP) & Other Inflammatory Markers 
  • Others 
  • Stool Tests 
  • Occult Blood Test 

By End User 

  • Hospitals & NICUs 
  • Pediatric Clinics 
  • Academic & Research Institutes 
  • Others 

By Region 

  • North America 
  • Europe 
  • Asia-Pacific 


Key Players 


  • Prolacta Bioscience Inc. 
  • Abbott Laboratories 
  • Mead Johnson Nutrition (Reckitt) 
  • Fresenius Kabi AG 
  • Danone S.A. 
  • Human Milk Banking Associations (Emerging Entities) 
  • Leading Academic and Research Hospitals 


Strategic Developments 


  • Introduction of precision nutrition solutions and AI-powered diagnostics 
  • Partnerships between biotechnology firms, research institutions, and neonatal care centers 
  • Increased investment in microbiome modulation therapies and biomarker innovation 


Download the complete TOC now! 


Case Study 

The report highlights collaborative efforts in North America and Europe, demonstrating the effectiveness of AI-enabled early detection tools, live biotherapeutic interventions, and human milk-based nutrition. These innovations have led to more accurate diagnoses, a reduction in NEC incidence, and improved survival outcomes for preterm infants. 

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Related Reports from BIS Research  

Nasal Polyposis Market

Mucopolysaccharidosis Market 

Pleural Effusion Market 


About BIS Research  

BIS Research is a global B2B market intelligence and advisory firm focusing on deep technology and related emerging trends, which can disrupt the market dynamics in the near future. We publish over 200 market intelligence studies annually, focusing on several deep technology verticals.    

Our strategic market analysis emphasizes market estimations, technology analysis, emerging high-growth applications, deeply segmented granular country-level market data, and other important market parameters useful in the strategic decision-making for senior management.     

BIS Research offers syndicate and custom studies and expert consultations to firms, providing them with specific and actionable insights on novel technology markets, business models, and competitive landscapes.    


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