Health & Safety Industry Today

Hereditary Angioedema Market to Witness Robust Growth by 2035 – BIS Research

The global HAE market is set to expand notably during the forecast period, with rising therapy demand, a wave of new drug approvals especially oral on-demand treatments and improved diagnostic techniques. Patient and physician awareness, combined with broader geographical access, are also key growth enablers.
Published 15 July 2025

What is hereditary angioedema? 

Hereditary angioedema is a rare genetic condition characterized by unpredictable episodes of severe swelling in various body parts, including extremities, airway, abdomen, and face. These swelling events are often triggered by trauma, stress, or occur without warning, and can become life-threatening if affecting the airway. 

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What Is the Market Outlook? 

The HAE market shows strong momentum: 

  • Advancements in diagnostics and growing patient/physician awareness are contributing to wider disease recognition. 
  • The pipeline of innovative therapies including both chronic and on‑demand treatments is broadening. 
  • Regulatory acceptance of oral therapies further expands treatment options. 


How Fast Is the Market Growing? 

The hereditary angioedema market is growing steadily as healthcare providers increasingly adopt newer therapies and diagnostics. Focus is shifting toward early identification and personalized treatment approaches, with both public and private sectors supporting development and access. 


How Will This Report Help You? 

Planning to Enter the Market? 

Understand therapy uptake projections and diagnostic evolution across key regions, including demand for both oral and injectable treatments. 

Analyzing the Competitive Landscape? 

Track market players and their strategies, including product launches, regulatory approvals, geographic expansion, and licensing deals. 

Seeking R&D Insights? 

Stay informed on clinical-stage innovations such as oral on-demand drugs, non-injectable formulations, and novel diagnostic techniques. 

Interested in Regional Market Trends? 

Access region-specific adoption rates and penetration dynamics, especially in countries with rising healthcare investments and improved disease awareness. 

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What Technologies Are Transforming the Market? 


  • Oral on‑demand therapies reshaping attack management 
  • Advanced injectables offering faster relief 
  • AI-integrated diagnostic tools enabling quicker identification 
  • Mobile care solutions enhancing rural access 
  • New classes of pharmacological agents under investigation 


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What’s Driving Demand, Opportunity and Barriers?

 

Drivers: 


  • Rising disease diagnosis and therapy demand 
  • Approval of convenient oral treatments 
  • Healthcare providers' increased awareness and testing 


Restraints: 


  • High treatment costs, especially for injectables 
  • Unequal access in rural and underserved regions 
  • Complexity in diagnosis due to rare disease status 


Opportunities: 


  • Oral therapy adoption and reimbursement innovations 
  • Growth in emerging regions through licensing agreements 
  • Public-private partnerships for awareness and early screening 


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How Is the Market Segmented? 

by Therapy Type 

•    C1-esterase inhibitor 

•    Bradykinin B2 receptor antagonist 

•    Kallikrein inhibitor 

•    Others 

by Region 

•    North America 

•    Europe 

•    Asia-Pacific 


Who Are the Leaders in the Hereditary Angioedema Market? 

• Adverum Biotechnologies, Inc. 

• Attune Pharmaceuticals 

• BioCryst Pharmaceuticals 

• CSL Behring 

• Ionis Pharmaceuticals, Inc. 

• KalVista Pharmaceuticals 

• Octapharma 

• Pharming Group 

• Takeda Pharmaceutical Company Limited 


Strategic Moves Shaping the Future: 


  • Launch of new oral HAE therapies transforming patient adherence 
  • Licensing partnerships to expand access in key regional markets 
  • Regulatory focus on patient-centric treatment formats 
  • Growing investments in diagnostics and digital health tools 


Case Study: Oral On‑Demand Therapy Breakthrough 

A leading biotech firm launched a novel oral therapy, the first of its kind approved for hereditary angioedema. The treatment demonstrated a fast onset of action comparable to injectable alternatives and is now being rolled out in partnership with regional pharma firms to reach broader populations. 

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Hyperkalemia Market 

Hyperopia Market 

Hypophosphatasia Market 


About BIS Research  

BIS Research is a global B2B market intelligence and advisory firm focusing on deep technology and related emerging trends, which can disrupt the market dynamics in the near future. We publish over 200 market intelligence studies annually, focusing on several deep technology verticals.    

Our strategic market analysis emphasizes market estimations, technology anaysis, emerging high-growth applications, deeply segmented granular country-level market data, and other important market parameters useful in the strategic decision-making for senior management.     

BIS Research offers syndicate and custom studies and expert consultations to firms, providing them with specific and actionable insights on novel technology markets, business models, and competitive landscapes.    


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