Glioblastoma Multiforme Treatment Market to Surpass USD 11.1 Billion by 2035, Driven by Surgery and Radiation Therapy

The global Glioblastoma Multiforme (GBM) treatment market is poised for significant growth over the next decade, driven by rising prevalence of aggressive brain tumors, advancements in therapeutic techniques, and increasing investments in oncology research. According to recent market insights, the industry is expected to expand from USD 3,612 million in 2024 to USD 11,101 million by 2035, registering a CAGR of 10.2% during the forecast period.

Surgery and radiation therapy remain the leading treatment segments, with both expected to grow at CAGRs of 10.5%. Geographically, the U.S. is projected to grow at 9.7%, followed by Germany at 9.5% and Japan at 9.0%.

Market Outlook: Strong Growth Over the Next Decade

The global Glioblastoma Multiforme treatment market is expected to reach USD 11,101 million by 2035, up from USD 3,612 million in 2024. During the forecast period from 2025 to 2035, the industry is projected to expand at a CAGR of 10.2%. This growth underscores the urgent need for advanced therapies to treat GBM, one of the most aggressive and lethal forms of brain cancer.

Increasing awareness about early detection, advancements in minimally invasive surgery, and the integration of radiation therapy with emerging immunotherapy and targeted drug approaches are fueling market expansion.

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Key Growth Drivers

1. Surgery as a Leading Treatment Option – The surgery segment is projected to grow at a CAGR of 10.5%, supported by innovations in neurosurgical techniques, robotic-assisted procedures, and precision-based excisions that improve patient outcomes.
2. Radiation Therapy Advancements – Radiation therapy is also likely to grow at 10.5% CAGR, driven by advanced delivery systems such as stereotactic radiosurgery (SRS), intensity-modulated radiation therapy (IMRT), and proton therapy.
3. Rising Incidence of Glioblastoma – Globally increasing prevalence of GBM, particularly among older adults, is driving demand for effective treatment options.
4. Investment in R&D – Pharmaceutical and biotechnology companies are heavily investing in clinical trials, drug development, and innovative combination therapies to improve survival rates and quality of life.
5. Adoption of Personalized and Precision Medicine – Integration of molecular diagnostics and genomic profiling enables tailored treatment strategies, which is boosting adoption of combination therapies alongside standard surgery and radiation therapy.

Competitive Landscape: Key Players and Strategies

The GBM treatment market is highly competitive, with global and regional players focusing on product innovation, strategic collaborations, and mergers and acquisitions to gain market share.

• Novocure: Focuses on tumor treating fields (TTF) technology for combination therapy with standard treatments.
• Roche: Invests in targeted therapies and immunotherapies for GBM treatment, collaborating with research institutions for clinical trials.
• Eisai Co., Ltd.: Offers combination therapies including chemotherapy and novel targeted drugs to enhance patient survival.
• Novartis AG: Active in precision medicine, integrating molecular profiling to improve GBM treatment outcomes.
• Other Key Players: Pfizer, Bristol-Myers Squibb, Merck, and Celgene are strengthening R&D pipelines, expanding global distribution, and forming strategic alliances to drive growth.

Emerging biotech startups are also contributing to innovation, particularly in the fields of immunotherapy, nanomedicine, and personalized drug delivery systems, prompting established companies to invest in collaborations and acquisitions.

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Regional Insights

• North America: The U.S. leads the market with a projected growth rate of 9.7%, supported by advanced healthcare infrastructure, high research investments, and a large patient population seeking specialized GBM treatments.
• Europe: Germany is expected to grow at 9.5%, driven by advanced healthcare systems, clinical research networks, and early adoption of novel therapies. Other European countries are showing moderate growth due to rising awareness and government initiatives.
• Asia-Pacific: Japan is projected to grow at 9.0%, with increased adoption of advanced neurosurgical procedures, radiotherapy, and emerging targeted treatments. Growth in China and India is supported by increasing healthcare access and investments in oncology infrastructure.
• Latin America & Middle East: Emerging markets are witnessing steady adoption of standard and advanced GBM treatments, supported by rising awareness and improving healthcare facilities.

Recent Market Developments

• Advancements in tumor treating fields (TTF) technology and combination therapies are enhancing treatment outcomes.
• Companies are expanding clinical trial networks to validate novel drug combinations and precision therapies.
• Integration of imaging, genomics, and AI-driven diagnostics is improving surgical planning and radiation therapy precision.
• Strategic partnerships between pharmaceutical companies, hospitals, and research institutes are accelerating access to new treatments globally.

These developments underscore the dynamic nature of the GBM treatment market and the importance of innovation to maintain a competitive edge.

Future Outlook

The GBM treatment market is expected to grow strongly over the next decade. Key trends shaping the market include:

• Expansion of surgery and radiation therapy segments with advanced techniques.
• Increased adoption of immunotherapy and targeted therapies in combination with standard treatments.
• Growth of personalized medicine approaches, leveraging genomic profiling and molecular diagnostics.
• Integration of AI, robotics, and digital healthcare platforms to enhance precision, efficacy, and patient outcomes.

Companies that effectively combine clinical innovation, technological advancement, and accessibility are likely to capture long-term growth in this rapidly evolving market.

About Fact.MR

Fact.MR is a global market research and consulting firm, providing actionable insights and strategic guidance across industries to support informed business decisions.

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