Gene Therapy for Neurodegenerative Diseases Market to Reach USD 15 Billion by 2035 with 20.1% CAGR

WiseGuy Reports, Sept. 2025 (Press Release) – The Gene Therapy for Neurodegenerative Diseases Market Global Outlook:

Gene Therapy for Neurodegenerative Diseases Market Size, Share & Industry Analysis By Therapeutic Area (Alzheimer's Disease, Parkinson's Disease, Amyotrophic Lateral Sclerosis, Huntington's Disease), By Gene Delivery Method (Adeno-Associated Virus, Lentivirus, Herpes Simplex Virus, Plasmid DNA), By Treatment Approach (In Vivo Therapy, Ex Vivo Therapy), By Type of Therapy (Single Gene Therapy, Multi Gene Therapy) and Regional Forecasts, 2025-2035

Key Profits for Gene Therapy for Neurodegenerative Diseases Market Industry Top Members and Stakeholders:

1. The Gene Therapy for Neurodegenerative Diseases Market report includes a plethora of information such as market dynamics scenario and opportunities during the forecast period.
2. Which regulatory trends at corporate-level, business-level, and functional-level strategies.
3. Which are the End-User technologies being used to capture new revenue streams in the near future.
4. The competitive landscape comprises share of key players, new developments, and strategies in the last three years.
5. One can increase a thorough grasp of Gene Therapy for Neurodegenerative Diseases Market dynamics by looking at prices as well as the actions of producers and users.

6 Comprehensive companies offering products, relevant financial information, recent developments, various Industry analysis methods, and strategies by these top players.

Gene Therapy for Neurodegenerative Diseases Market Overview

The Gene Therapy for Neurodegenerative Diseases Market is gaining momentum as a breakthrough treatment approach for disorders such as Alzheimer's, Parkinson’s, Huntington’s disease, and amyotrophic lateral sclerosis (ALS). With an estimated market size of USD 2,000 million in 2024, the sector is set for substantial growth, reaching USD 2,400 million by 2025. The market is projected to reach USD 15 billion by 2035, reflecting a robust compound annual growth rate (CAGR) of 20.1% from 2025 to 2035. This growth is driven by the rising prevalence of neurodegenerative diseases, advances in gene editing technologies, and significant investments in research and development (R&D).

Market Segmentation

The Gene Therapy for Neurodegenerative Diseases Market is segmented across various dimensions, including therapeutic area, gene delivery methods, treatment approaches, types of therapy, and regions. Each of these segments offers unique insights into the trends and developments shaping the market.

1. Therapeutic Area: Neurodegenerative diseases like Alzheimer's and Parkinson's represent the largest share of the market. These conditions have high unmet medical needs, as existing therapies primarily address symptoms rather than the underlying causes. Gene therapies targeting these diseases aim to restore normal cellular function, providing more effective long-term treatment options.
2. Gene Delivery Method: Gene delivery is a critical component of gene therapy. Viral vectors, particularly adeno-associated viruses (AAV), are commonly used due to their ability to deliver genetic material efficiently to specific cells. Non-viral methods, including CRISPR-Cas9 and nanoparticles, are also being explored as promising alternatives to traditional viral-based therapies.
3. Treatment Approach: Gene therapy approaches can be categorized into in vivo and ex vivo methods. In vivo therapy involves directly delivering the therapeutic gene into the patient’s body, while ex vivo therapy requires cells to be removed, genetically modified outside the body, and then reintroduced into the patient. Both methods are advancing in clinical trials, with a focus on improving efficiency, safety, and long-term efficacy.
4. Type of Therapy: Gene therapies can be classified into somatic gene therapy and germline gene therapy. Somatic gene therapy targets non-reproductive cells and is currently the preferred method for neurodegenerative diseases. Germline gene therapy, which modifies genetic material in reproductive cells, is not yet widely used due to ethical and safety concerns.
5. Regional: The market is geographically diverse, with key regions including North America, Europe, APAC, South America, and the Middle East & Africa (MEA). The United States, Canada, Germany, the UK, France, China, India, Japan, and South Korea are expected to lead the market due to their strong healthcare infrastructures, regulatory support, and ongoing biotech research initiatives.

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Key Market Dynamics

Several key factors are driving the growth of the Gene Therapy for Neurodegenerative Diseases Market. The most significant driver is the growing prevalence of neurodegenerative diseases worldwide. As the global population ages, the incidence of diseases like Alzheimer's and Parkinson's is increasing, leading to an urgent need for effective treatments.

Advancements in gene editing technologies, such as CRISPR-Cas9, are making gene therapy more precise and effective. These technologies allow for targeted gene modification, increasing the chances of successful treatments. Additionally, the high unmet medical needs in the neurodegenerative space are pushing researchers and pharmaceutical companies to focus on developing innovative gene therapies.

Regulatory support for gene therapies is also helping to accelerate market growth. In recent years, several gene therapies have received breakthrough therapy designations and accelerated approvals from regulatory bodies such as the FDA and EMA. This support is essential for bringing new treatments to market more quickly and addressing critical patient needs.

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Competitive Landscape

The competitive landscape of the Gene Therapy for Neurodegenerative Diseases Market includes key players such as Novartis, Pfizer, Bluebird Bio, Takeda Pharmaceutical, Roche, Spark Therapeutics, Biogen, Editas Medicine, Sanofi, and Neuralstem, among others. These companies are investing heavily in R&D to develop gene therapies that target the root causes of neurodegenerative diseases.

Gene therapy leaders like Novartis and Biogen are at the forefront, with ongoing clinical trials and partnerships with biotech firms to expand their portfolios. The increasing focus on personalized medicine has created new opportunities for companies to differentiate themselves by offering therapies tailored to specific genetic mutations or patient profiles.

The growing investment in biotech research is fueling the development of next-generation therapies. With the increasing success of early-stage clinical trials, more companies are entering the market, intensifying competition and driving innovation.

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Market Opportunities

The Gene Therapy for Neurodegenerative Diseases Market offers numerous opportunities, particularly due to the increasing prevalence of neurodegenerative disorders and advances in gene editing technologies. The demand for personalized medicine is also rising, as patients and healthcare providers seek therapies tailored to specific genetic profiles. As gene therapy becomes more effective, it is expected to gain broader acceptance among patients and healthcare providers.

The growing investment in biotech research is another key opportunity. Increased funding is enabling the development of innovative therapies, which could lead to breakthroughs in treating neurodegenerative diseases. Additionally, the expanding regulatory approvals for gene therapies in various regions are opening new markets for these treatments.

Conclusion

The Gene Therapy for Neurodegenerative Diseases Market is poised for rapid growth, driven by the increasing prevalence of neurodegenerative diseases, advancements in gene editing technologies, and growing investments in biotech research. As the market continues to evolve, companies that focus on innovative treatments and personalized medicine will be well-positioned for success. The next decade promises to bring significant advancements in the way neurodegenerative diseases are treated, creating a substantial opportunity for both pharmaceutical companies and patients alike.

Reasons To Buy The Gene Therapy for Neurodegenerative Diseases Market Report:

➼ In-depth analysis of the Gene Therapy for Neurodegenerative Diseases Market on the global and regional levels.

➼ Major changes in market dynamics and competitive landscape.

➼ Segmentation on the basis of type, application, geography, and others.

➼ Historical and future market research in terms of size, share growth, volume, and sales.

➼ Major changes and assessment in market dynamics and developments.

➼ Emerging key segments and regions

➼ Key business strategies by major market players and their key methods

Avail This Gene Therapy for Neurodegenerative Diseases Market Language Pages Here:

神経変性疾患の遺伝子治療市場規模 | Marktanteil der Gentherapie für neurodegenerative Erkrankungen | Analyse du marché de la thérapie génique pour les maladies neurodégénératives | 신경퇴행성 질환에 대한 유전자 치료 시장 분석 | 神经退行性疾病基因治疗市场概况 | Tendencias del mercado de la terapia génica para enfermedades neurodegenerativas

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