Biosurgery Market to Reach US$ 29.15 Billion by 2031, Growing at 7.1% CAGR

United States of America – December 10, 2025 – According to The Insight Partners, the biosurgery market is on a promising path, projected to hit US$ 29.15 billion by 2031 with a steady CAGR of 7.1% from 2025 to 2031. This expansion goes beyond numbers—it's about surgeons having better tools to help patients heal faster, with fewer complications, and return to their lives sooner after surgery.​

Market overview

Biosurgery involves biologically derived products that support natural healing processes during and after surgery, from stopping bleeding to preventing scar tissue buildup. For patients facing major procedures, these tools mean less time in recovery, reduced pain, and a smoother path back to work, family, or hobbies—real differences that families notice every day.​

The biosurgery market has matured as minimally invasive techniques become standard, with products designed to work alongside robotic systems and laparoscopic tools. Regions like North America lead due to high procedure volumes, while Asia-Pacific grows fastest as healthcare access improves and surgeons adopt advanced hemostats and sealants.​

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Market stats and growth drivers

Industry forecasts place the biosurgery market on a mid-single-digit growth trajectory, with multiple analyses confirming CAGRs around 6–8% through the decade, matching the 7.1% outlook for 2025–2031. Orthopedic and general surgeries drive much of this, fueled by aging populations needing joint replacements and rising obesity leading to more abdominal procedures.​

Healthcare systems worldwide prioritize products that cut blood loss, hospital stays, and readmissions, making biosurgery a cost-effective choice over traditional methods. Strong reimbursement, surgeon training programs, and evidence from clinical trials further accelerate adoption, turning innovative products into everyday operating room staples.​

Segmentation by product

The biosurgery market segments by product into categories that address specific surgical challenges, each improving outcomes in tangible ways.​

•        Bone graft substitutes - Bone graft substitutes lead volumes, especially in orthopedics and spine surgery, offering alternatives to patient-harvested bone with easier handling and reduced donor-site pain. Patients often recover quicker, avoiding the added discomfort of a second surgical site.​

•        Soft tissue attachments - These help secure meshes and repairs in hernia or pelvic surgeries, promoting tissue integration and strength over time. For active individuals, this means returning to exercise without worrying about recurrence.​

•        Surgical sealants & adhesives - Sealants and adhesives provide watertight closures in vascular or lung procedures, minimizing air leaks or bleeding that could prolong recovery. Surgeons value their quick application, while patients appreciate fewer drains and earlier discharge.​

•        Adhesion barriers - Adhesion barriers prevent scar tissue from binding organs post-abdominal surgery, reducing risks of chronic pain or bowel obstructions. This is especially meaningful for women after gynecological procedures, helping avoid long-term complications.​

•        Hemostatic agents - Hemostats control bleeding rapidly in trauma or high-volume surgeries, critical for patient stability and shorter operative times. In emergencies, they give surgical teams confidence to focus on the procedure rather than persistent oozing.​

Segmentation by application

Biosurgery products serve diverse applications, tailored to the unique demands of each surgical field.​

•        Orthopedic surgery - Orthopedics claims the largest share, with bone grafts and hemostats supporting joint replacements and fractures amid rising sports injuries and osteoporosis. Patients get back on their feet faster, often walking the same day.​

•        General surgery - In general surgery, sealants and adhesion barriers shine in laparoscopies for hernias or gallbladders, cutting infection risks and ileus. Everyday procedures become even safer, letting patients resume normal eating sooner.​

•        Neurological surgery - Neuro applications use sealants for dural repairs and hemostats in tumor resections, protecting delicate brain tissue. Precision here supports better neurological recovery and quality of life.​

•        Cardiovascular surgery - Cardiac procedures rely on sealants for anastomoses and hemostats during bypasses, growing fastest due to minimally invasive trends. Shorter clamp times mean less heart stress and quicker rehab.​

•        Gynecological surgery - In gynecology, adhesion barriers prevent post-op scarring after hysterectomies or endometriosis treatments. Women benefit from reduced fertility issues or chronic pelvic pain.​

•        Other applications - Thoracic, urological, and reconstructive surgeries round out usage, with versatile hemostats and sealants adapting across ENT, dental, and trauma cases.​

Key market trends

Biosurgery trends emphasize integration with advanced surgery, like robotics and 3D printing for custom grafts. Biologics dominate but synthetics grow for consistency and shelf life, while combination products merge hemostasis with sealing.​

Surgeons seek easy-to-use formats—sprays, patches, powders—that fit laparoscopic workflows, reducing training time. Sustainability pushes bioresorbable options, and real-world evidence from registries builds trust in long-term efficacy.​

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Opportunities and growth pockets

The biosurgery market brims with potential for innovators focusing on unmet needs.​

• Emerging markets offer volume as elective surgeries rise with middle-class growth.​
• Minimally invasive and outpatient shifts favor quick-deploy products for ASCs.​
• Personalized biologics from stem cells or patient-matched grafts target complex reconstructions.​

Companies blending strong clinical data with surgeon education will capture loyalty, especially in high-growth cardio and neuro segments.​

Market leaders and key companies

Established medtech firms dominate the biosurgery market through broad portfolios and global reach.​

• B. Braun Melsungen AG excels in hemostats and sealants for general and ortho use.​
• Baxter leads with adhesion barriers and comprehensive surgical care lines.​
• BD (Becton Dickinson) offers hemostatic agents and innovative matrices.​
• CryoLife, Inc. specializes in tissue-based grafts for cardio and vascular repairs.​
• Ethicon US, LLC. (Johnson & Johnson) dominates sealants and energy devices.​
• Integra LifeSciences focuses on neuro dural sealants and regenerative matrices.​
• Ocular Therapeutix, Inc. advances hydrogel sealants for ophthalmic crossover.​
• SIRAKOSS innovates in bioresorbable barriers.​
• Stryker powers orthopedics with bone grafts and trauma solutions.​

These players compete on evidence, usability, and partnerships, ensuring biosurgery evolves with surgical needs.​

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