Adrenocortical Carcinoma Market Set to Grow by 2035– BIS Research

What is adrenocortical carcinoma? 

ACC is a rare, aggressive cancer originating in the adrenal cortex, often presenting with hormone-related syndromes like Cushing’s. Incidence is about 1–2 per million annually, with mixed bimodal distribution (children under 5 and adults 30–40 years). Prognosis remains poor; 5‑year overall survival is approximately 50%. 

What Is the Market Outlook? 

Hospitals, research institutes, and pharmaceutical players are shifting toward personalized and targeted therapies. Diagnostic innovations and clinic partnerships are broadening scope. Recent developments also include significant funding and collaboration activities. 

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How Fast Is the Market Growing? 

The adrenocortical carcinoma market is witnessing steady momentum driven by rising awareness, expanding clinical trials, and increasing adoption of targeted therapies. Though the condition is rare, healthcare systems are investing in rare cancer solutions, and companies are actively advancing treatment pipelines. While the exact growth rate is not disclosed, the market outlook remains optimistic across developed and emerging regions. 

How Will This Report Help You? 

Entering the Market? 

• Evaluate therapy demand across regions (Americas, Europe, Asia‑Pacific, Middle East & Africa), key segments (surgery, chemotherapy, targeted therapy, radiation), and end-user groups (hospitals, clinics, research centers). 

Analyzing the Competitive Landscape? 

• Identify and benchmark leading players HRA Pharma, Cytovation, Exelixis, Bristol‑Myers Squibb, among others including their funding, partnerships, and clinical pipeline. 

Seeking R&D Insights? 

• Gain exposure to CY‑101 trials by Cytovation, FGFR inhibitor ARQ 087, and other emerging targeted therapies in development. 

Interested in Regional Market Trends? 

• The Americas (especially North America) lead the market due to strong healthcare systems; Europe follows. Asia‑Pacific is the fastest‑growing region; the Middle East & Africa represents the smallest share. 

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What Technologies Are Transforming the Market? 

• Targeted therapies (e.g. CY‑101, ARQ 087) 
• Advanced diagnostics (molecular testing, histopathology) 
• Imaging and surgical improvements (laparoscopic/open surgery)  

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What’s Driving Demand, Opportunity and Barriers? 

Drivers: 

• Rising prevalence of ACC 
• Growth in rare-cancer research and trial activity 
• Advancements in diagnosis and personalized medicine 

Restraints: 

• High treatment and diagnostic costs 
• Limited expert availability (note: misdiagnosis rate in Germany was ~13%) 

Opportunities: 

• Expansion of targeted and hormone-based therapies 
• New drug launches and clinical collaborations 
• Increasing awareness and diagnostic accuracy

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Who Are the Leaders in the Spinal Navigation Market? 

• HRA Pharma 

• Cytovation 

• Exelixis, Inc. 

• Bristol-Myers Squibb 

Strategic Moves Shaping the Future 

Funding & Clinical Trials:

• April 2025: Cytovation raised USD 6M for CY‑101 clinical advancement 
• January 2025: Cytovation partnered with Cancer Research UK & Norwegian Cancer Society 

Partnerships & Approvals: 

• Pipeline coordination and biotech alliances expanding trial reach and regulatory traction

Case Study 

Cytovation & CY‑101: 

In April 2025, Cytovation received USD 6 million funding for its CY‑101 molecule targeting ACC. A related partnership with Cancer Research UK and Norwegian Cancer Society, initiated in January 2025, is advancing CY‑101 into a Phase 2 multinational clinical trial . 

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Coagulation Factor Deficiency Market 

Critical Limb Ischemia Market 

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About BIS Research  

BIS Research is a global B2B market intelligence and advisory firm focusing on deep technology and related emerging trends, which can disrupt the market dynamics in the near future. We publish over 200 market intelligence studies annually, focusing on several deep technology verticals.    

Our strategic market analysis emphasizes market estimations, technology analysis, emerging high-growth applications, deeply segmented granular country-level market data, and other important market parameters useful in the strategic decision-making for senior management.     

BIS Research offers syndicate and custom studies and expert consultations to firms, providing them with specific and actionable insights on novel technology markets, business models, and competitive landscapes.    

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