Sacubitril API Market Set to Reach USD 1,200 Million by 2035, at 5.6% CAGR

The global Sacubitril API market has experienced significant growth in recent years, driven by the increasing prevalence of cardiovascular diseases and the rising demand for effective heart failure treatments. Sacubitril, an active pharmaceutical ingredient (API), is a key component in the formulation of angiotensin receptor-neprilysin inhibitors (ARNIs), which are used to treat patients with chronic heart failure.

Market Overview

The Sacubitril API Market was valued at USD 700 million in 2024. It is projected to expand from USD 700 million in 2025 to USD 1,200 million by 2035, registering a CAGR of approximately 5.6% over the forecast period (2025–2035). This growth is attributed to the expanding patient population requiring heart failure treatments and the increasing adoption of Sacubitril-based therapies.

Key Market Drivers

• Rising Incidence of Cardiovascular Diseases: The global rise in lifestyle-related diseases, such as hypertension and diabetes, has led to an increase in cardiovascular conditions, thereby boosting the demand for heart failure treatments.
• Advancements in Pharmaceutical Research: Ongoing research and development efforts have led to the introduction of novel Sacubitril-based formulations, enhancing treatment efficacy and patient outcomes.
• Technological Innovations in API Production: The adoption of advanced manufacturing technologies, including continuous flow manufacturing and biocatalysis, has improved the efficiency and cost-effectiveness of Sacubitril API production.

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Competitive Landscape

The Sacubitril API market is characterized by the presence of several key manufacturers and suppliers globally. Notable players include:

• Dr. Reddy's Laboratories: Based in India, Dr. Reddy's is a leading manufacturer and supplier of Sacubitril API, catering to markets in the US, Europe, and emerging economies.
• LGM Pharma: An API distributor that supplies Sacubitril APIs as per CGMP with Drug Master File (DMF) support, subject to availability and manufacturer requirements.
• Metrochem API Private Limited: An Indian company that delivers customized volume and quality products to customers worldwide, adhering to stringent quality standards.

These companies play a crucial role in ensuring the steady supply of Sacubitril APIs to meet the growing global demand.

Key Companies in the Global Sacubitril API Market include:

• Sandoz

• Eli Lilly and Company

• Aurobindo Pharma

• Boehringer Ingelheim

• Amgen

• Mylan

• Teva Pharmaceutical Industries

Regional Insights

The Asia-Pacific region, particularly India and China, has emerged as a significant hub for Sacubitril API production due to the presence of cost-effective manufacturing facilities and a skilled workforce. These countries export Sacubitril APIs to various international markets, including North America, Europe, and Latin America.

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Challenges and Opportunities

Despite the positive growth trajectory, the Sacubitril API market faces challenges such as regulatory hurdles, price fluctuations, and the need for continuous innovation to meet evolving patient needs. However, these challenges also present opportunities for market players to invest in research and development, explore new markets, and develop cost-effective manufacturing processes to maintain a competitive edge.

Conclusion

The Sacubitril API market is poised for continued growth, driven by the increasing prevalence of cardiovascular diseases and advancements in pharmaceutical research and manufacturing technologies. Stakeholders in the healthcare and pharmaceutical sectors must stay abreast of market trends and regulatory developments to capitalize on emerging opportunities and address the challenges inherent in this dynamic market.

Translation of the Report in Different Languages:

 サクビトリル原薬市場 | Sacubitril API-Markt | Marché de l'API Sacubitril | Sacubitril API 시장 | Sacubitril API 市场 | Mercado de API de Sacubitril

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