Chemicals Industry Today

Avenanthramides Market to Grow at 7.08% Annually, Reaching $4.5 Billion by 2032

This growth is fueled by rising awareness of the health benefits associated with Avenanthramides, particularly their anti-inflammatory and antioxidant properties
Published 13 June 2025

In recent years, the search for natural compounds with potent health benefits has brought increasing attention to avenanthramides — unique polyphenolic compounds found almost exclusively in oats (Avena sativa). These bioactive molecules, although lesser known compared to vitamins or flavonoids, are emerging as valuable components in both nutrition and skincare due to their antioxidant, anti-inflammatory, anti-itching, and even anti-cancer properties. As consumers lean toward functional foods and naturally derived wellness solutions, avenanthramides are steadily gaining recognition across multiple sectors.

Avenanthramides Market Size was estimated at 2.43 (USD Billion) in 2023. The Avenanthramides Market Industry is expected to grow from 2.6 (USD Billion) in 2024 to 4.5 (USD Billion) by 2032. The Avenanthramides Market CAGR (growth rate) is expected to be around 7.08% during the forecast period (2024 - 2032)


Antioxidant and Anti-Inflammatory Powerhouse

One of the most compelling aspects of avenanthramides is their role as powerful antioxidants. They help scavenge free radicals and prevent oxidative damage to cells, which is a major contributor to aging and chronic diseases like cancer, diabetes, and cardiovascular disorders.

Beyond neutralizing free radicals, avenanthramides possess strong anti-inflammatory effects. They inhibit the release of pro-inflammatory cytokines and reduce the activity of nuclear factor kappa B (NF-κB), a key regulator in the body's inflammatory response. This makes them particularly beneficial in managing conditions related to chronic inflammation.

Cardiovascular Health Benefits

The benefits of oats for heart health are well-documented, largely due to their soluble fiber content (beta-glucans). However, avenanthramides add another layer to this cardio-protective profile. Studies show that avenanthramides can enhance nitric oxide production, which helps dilate blood vessels and improve blood flow. This vasodilatory effect contributes to reduced blood pressure and lower risk of atherosclerosis.

Additionally, avenanthramides may inhibit the oxidation of LDL (low-density lipoprotein) cholesterol — a critical step in the development of plaque in arteries. By preventing LDL oxidation, these compounds help reduce the risk of heart disease and stroke. 

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Skin Health and Dermatological Applications

Avenanthramides have long been recognized for their benefits in dermatology, especially in soothing skin irritation, itching, and redness. This is why colloidal oatmeal, which retains avenanthramide content, is a popular ingredient in creams, lotions, and therapeutic bath products.

These compounds modulate the skin’s immune response, helping reduce inflammation and histamine-induced itch. Their anti-irritant and calming effects make them ideal for managing eczema, psoriasis, allergic reactions, and even sunburn. Their natural origin and compatibility with sensitive skin have made avenanthramides a staple in over-the-counter dermatological treatments.

Anti-Itch and Anti-Allergic Effects

Avenanthramides help inhibit the release of histamines, which are central to allergic reactions and skin irritation. This histamine-suppressing action is critical in reducing itch and redness associated with allergic responses and conditions like atopic dermatitis.

The mechanism involves modulation of mast cells and suppression of pro-inflammatory mediators — making avenanthramides a natural and safe option for long-term use in managing itching without the side effects associated with corticosteroids or antihistamines.

Role in Exercise Recovery

Another emerging area of interest is the role of avenanthramides in post-exercise muscle recovery. Research indicates that these compounds can reduce markers of muscle damage and inflammation following intense physical activity. By minimizing oxidative stress and inflammation, avenanthramides may help improve recovery time and enhance athletic performance — which opens up new possibilities for oat-derived supplements in the sports nutrition market.

Cancer-Fighting Potential

Although research is still in early stages, avenanthramides have shown promise in cancer prevention. They exhibit antiproliferative effects on cancer cells by inducing apoptosis (programmed cell death) and inhibiting cancer cell growth. These properties are especially noted in colorectal and breast cancer models. Their dual action of reducing oxidative damage and modulating inflammation further supports their potential as natural chemopreventive agents.

Avenanthramides in the Food and Supplement Market

With the growing trend toward plant-based, clean-label ingredients, avenanthramides present a compelling opportunity for food and nutraceutical manufacturers. Their presence can enhance the functional profile of oat-based cereals, snack bars, beverages, and supplements.

Moreover, as consumers increasingly recognize oats for more than just their fiber content, companies are beginning to market products that emphasize their avenanthramide content. Standardization of avenanthramide levels and extraction techniques is also gaining traction, enabling formulation of concentrated supplements for targeted health benefits. 

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Key Companies in the Avenanthramides Market Include:

  • Grain Millers
  • U.S. Commodities
  • KTC Edibles
  • Glucanova
  • Oats3
  • Blommer Chocolate
  • Lactulose
  • Kemin Industries
  • International Avena Group
  • Taura Natural Ingredients
  • Cargill
  • Healthy Food Ingredients
  • Bioactor
  • DSM
  • Nestle

Avenanthramides might still be under the radar for many, but their remarkable health-promoting properties are driving a quiet revolution in nutrition and skincare. From heart health and muscle recovery to soothing irritated skin and fighting inflammation, these oat-derived compounds are proving to be powerful allies in holistic wellness. 

Translation of the Report in Different Languages 

Marché des Avenanthramides | Markt für Avenanthramide | 아베난트라마이드 시장 | 燕麦生物碱市场 | Mercado de avenantramidas | アベナンスラミデス市場 

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